Local knowledge helps determine protein structures
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چکیده
منابع مشابه
Local knowledge helps determine protein structures.
T he nuclear Overhauser effect (NOE) has been the workhorse of structural studies of macromolecules in solution by NMR spectroscopy. The NOE is a measure of the rate of magnetization transfer between nuclei, induced by modulation of the magnetic dipole–dipole coupling between nuclear spins by overall tumbling of the molecule in solution (1). The efficiency of magnetization transfer via this mec...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0801069105